Risperidone is a dopamine D2, 5-HT2A, alpha1-adrenoceptor, and histamine-1 receptor antagonist that has been used in the treatment of schizophrenia, acute and chronic psychosis, mania and also Tourette’s syndrome, autism, ADHD and learning disability.

Common or very common side effects include: Agitation; amenorrhoea; arrhythmias; constipation; dizziness; drowsiness; dry mouth; erectile dysfunction; fatigue; galactorrhoea; gynaecomastia; hyperglycaemia; hyperprolactinaemia; hypotension (dose-related); insomnia; leucopenia; movement disorders; muscle rigidity; neutropenia; parkinsonism; postural hypotension (dose-related); QT interval prolongation; rash; seizure; tremor; urinary retention; vomiting & weight increase. The full list of side effects can be seen in the summary of product characteristics. If your child feels faint or dizzy, has heart problems (eg racing heart) a temperature of greater than 38.0C or stiff muscles they may be having a serious reaction to risperidone and you should seek medical advice immediately.


Authored by: Dr Tim Ubhi

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